Background:

Tetrodotoxin-resistant channel that mediates the voltage-dependent sodium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a sodium-selective channel through which sodium ions may pass in accordance with their electrochemical gradient. Plays a role in neuropathic pain mechanisms.

Specificity:

NaV1.8 polyclonal antibody detects endogenous levels of NaV1.8 protein.

Alternative names:

PN3, Scn10a, Sns, hPN3, mPN3, Peripheral nerve sodium channel 3, Pn3 (gene name), PN3, SCN10A, SCNAA, Sensory neuron sodium channel, Sns (gene name), SNS, Sodium channel protein type 10 subunit alpha, Sodium channel protein type X alpha subunit, Sodium channel protein type X subunit alpha, Voltage-gated sodium channel alpha subunit Nav1.8, Voltage-gated sodium channel subunit alpha Nav1.8,

Species reactivity:

Mouse, Rat

Host:

Rabbit

Ig type:

Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Immunogen:

Recombinant protein

Purification & Purity:

ProA affinity purified

Molecular weight:

220 kDa

Applications:

WB IHC

Usage:

WB:1:100-1:500 IHC:1:50-1:200

Storage:

Store at +4°C after thawing. Aliquot store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.

Precautions:

For research use only, not for use in diagnostic procedure.

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Email: info@sobekbio.com

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