Background:

The mucins are a family of highly glycosylated, secreted proteins with a basic structure consisting of a variable number of tandem repeats (VNTRs) encoded by 60 base pairs (Mucin 1), 69 base pairs (Mucin 2) and 51 base pairs (Mucin 3). The number of repeats is highly polymorphic and varies among different alleles. Mucin 1 proteins are expressed as type I membrane proteins in addition to secreted forms. Mucin 1 is aberrantly expressed in epithelial tumors including breast carcinomas. Mucin 2 coats the epithelia of the intestines and airways and is associated with colonic tumors. Mucin 3 is a major com-ponent of various mucus gels and is broadly expressed in normal and tumor cells.

Specificity:

MUC2 polyclonal antibody detects endogenous levels of MUC2 protein.

Alternative names:

MUC-2, MUC2, Intestinal mucin 2, Intestinal mucin-2, MLP, MUC 2, MUC-2, Muc2, MUC2, Mucin 2, Mucin 2 intestinal, Mucin 2 intestinal/tracheal, Mucin 2 oligomeric mucus/gel forming, Mucin 2 precursor, Mucin 2 tracheal, Mucin like protein, Mucin-2, Mucin2, SMUC,

Species reactivity:

Human, Rat

Host:

Rabbit

Ig type:

Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Immunogen:

recombinant protein

Purification & Purity:

ProA affinity purified

Molecular weight:

540 kDa

Applications:

WB ICC/IF IHC FC

Usage:

WB:1:500-1:1,000 ICC:1:100-1:500 IHC:1:50-1:200 FC:1:50-1:100

Storage:

Store at +4°C after thawing. Aliquot store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.

Precautions:

For research use only, not for use in diagnostic procedure.

More info:

Email: info@sobekbio.com

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