Background:

Binds to the mitochondrial light strand promoter and functions in mitochondrial transcription regulation. Required for accurate and efficient promoter recognition by the mitochondrial RNA polymerase. Promotes transcription initiation from the HSP1 and the light strand promoter by binding immediately upstream of transcriptional start sites. Is able to unwind and bend DNA. Required for maintenance of normal levels of mitochondrial DNA. May play a role in organizing and compacting mitochondrial DNA. target DNA. Interacts with TFB1M and TFB2M.

Specificity:

mtTFA polyclonal antibody detects endogenous levels of mtTFA protein.

Alternative names:

mtTFA, MtTF1, TCF-6, TFAM, TCF6, TCF6L2, anscription factor 6-like 1, Mitochondrial transcription factor 1, mitochondrial transcription factor A, MtTF1, mtTFA, TCF 6, TCF-6, TCF6, TCF6L1, TCF6L2, TCF6L3, TFAM, TFAM, Transcription factor 6, Transcription factor 6 like 2 (mitochondrial transcription factor), Transcription factor 6 like 2, Transcription factor 6-like 2, transcription factor 6-like 3, Transcription factor A, mitochondrial, Transcription factor A, mitochondrial, Transcription factor A, mitochondrial precursor,

Species reactivity:

Human

Host:

Rabbit

Ig type:

Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Immunogen:

Recombinant protein

Purification & Purity:

ProA affinity purified

Molecular weight:

Applications:

WB ICC/IF IHC IP

Usage:

WB:1:200-1:500 ICC/IF:1:50-1:200 IHC:1:50-1:200 IP:1:10-1:50

Storage:

Store at +4°C after thawing. Aliquot store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.

Precautions:

For research use only, not for use in diagnostic procedure.

More info:

Email: info@sobekbio.com

Orders:

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