Background:

Msi2 (musashi homolog 2), also known as MSI2H, is a 328 amino acid protein that localizes to the cytoplasm and contains two RRM (RNA recognition motif) domains. Expressed ubiquitously at low levels, Msi2 functions as an RNA binding protein that, by regulating the expression of target mRNAs, is thought to play a role in the proliferation and maintenance of stem cells within the central nervous system. Msi2 is subject to post-translational phosphorylation and is upregulated in response to brain injury, suggesting a role in healing and brain tissue regeneration. Chromosomal aberrations involving the Msi2 gene are associated with the progression of chronic myeloid leukemia. Multiple isoforms of Msi2 exist due to alternative splicing events.

Specificity:

MSI2 polyclonal antibody detects endogenous levels of MSI2 protein.

Alternative names:

Musashi-2, MSI2, FLJ36569, MGC3245, Msi2, MSI2/HOXA9 fusion gene, included, MSI2H, MSI2H, Musashi 2, Musashi homolog 2, Musashi RNA binding protein 2, Musashi, Drosophila, homolog of, 2, Musashi-2, RNA binding protein Musashi homolog 2, RNA-binding protein Musashi homolog 2, WD 40 repeat protein MSI2,

Species reactivity:

Human, Mouse, Rat

Host:

Rabbit

Ig type:

Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Immunogen:

Recombinant protein.

Purification & Purity:

Protein affinity purified.

Molecular weight:

35/37 kDa

Applications:

WB ICC IHC FC

Usage:

WB:1:500-1:1,000 ICC:1:50-1:200 IHC:1:50-1:200 FC:1:50-1:100

Storage:

Store at +4°C after thawing. Aliquot store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.

Precautions:

For research use only, not for use in diagnostic procedure.

More info:

Email: info@sobekbio.com

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