Background:

G-protein coupled receptor for glutamate. Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of down-stream effectors. Signaling activates a phosphatidylinositol-calcium second messenger system. May participate in the central action of glutamate in the CNS, such as long-term potentiation in the hippocampus and long-term depression in the cerebellum.

Specificity:

mGluR1 polyclonal antibody detects endogenous levels of mGluR1 protein.

Alternative names:

mGluR1, GRM1, Glutamate receptor metabotropic 1, glutamate receptor, metabotropic 1, GPRC1A, GRM1, GRM1-Alpha, GRM1, GRM1A, Metabotropic glutamate receptor 1, mGlu1, mGluR1, MGLUR1-Alpha, MGLUR1A, SCAR13,

Species reactivity:

Human, Mouse, Rat

Host:

Rabbit

Ig type:

Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Immunogen:

recombinant protein

Purification & Purity:

ProA affinity purified

Molecular weight:

200 kDa

Applications:

WB IHC

Usage:

WB:1:500-1:1,000 IHC:1:50-1:200

Storage:

Store at +4°C after thawing. Aliquot store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.

Precautions:

For research use only, not for use in diagnostic procedure.

More info:

Email: info@sobekbio.com

Orders:

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