Background:

LRG1 (leucine-rich alpha-2-glycoprotein), also known as LRG, is a 347 amino acid secreted protein that contains eight LRR (leucine-rich repeats) and one LRRCT domain. The leucine-rich repeat (LRR) family of proteins, including LRG1, have been shown to be involved in protein-protein interaction, signal transduction, cell adhesion and development. Found mainly in plasma, LRG1 is expressed during granulocyte differentiation. The gene that encodes LRG1 consists of nearly 3,000 bases and maps to human chromosome 19p13.3. Chromosome 19 consists of over 63 million bases, houses approximately 1,400 genes and is recognized for having the greatest gene density of the human chromosomes. It is the genetic home for a number of immunoglobulin (Ig) superfamily members, including the killer cell and leukocyte Ig-like receptors, a number of ICAMs, the CEACAM and PSG families and Fc receptors (FcRs).

Specificity:

LRG1 polyclonal antibody detects endogenous levels of LRG1 protein.

Alternative names:

LRG, LRG1, LRG, 1300008B03Rik, 2310031E04Rik, A2GL, A2GL, HMFT1766, Leucine rich alpha 2 glycoprotein, Leucine-rich alpha-2-glycoprotein 1, Leucine-rich alpha-2-glycoprotein, Leucine-rich alpha-2-glycoprotein precursor, LRG, LRG1,

Species reactivity:

Human

Host:

Rabbit

Ig type:

Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Immunogen:

Recombinant protein

Purification & Purity:

ProA affinity purified

Molecular weight:

38 kDa

Applications:

WB IHC IP

Usage:

WB:1:500-1:2,000 IHC:1:50-1:200 IP:1:10-1:50

Storage:

Store at +4°C after thawing. Aliquot store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.

Precautions:

For research use only, not for use in diagnostic procedure.

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