Lipocalin-2 polyclonal antibody BS90800
Specifications
| 50ul/100ul |
Background:
In addition to the monomeric mammalian progelatinase, two additional forms of progelatinase have been identified. The shorter of these additional forms is a covalently linked, disulfide-bridged protein that heterodimerizes with a short protein; an α2-Microglobulin-related protein known as neutrophil gelatinase-associated lipocalin (NGAL), which is moderately expressed in breast and lung tissues. NGAL belongs to the lipocalin family and has a high degree of similarity with rat α2-Microglobulin-related protein and mouse protein 24p3. NGAL is able to bind a derivative of the bacterial chemotactic peptide, suggesting that it has important immuno-modulatory functions. NGAL has been described as an inflammatory protein; it is released into the circulation as a result of the inflammatory activation of leukocytes initiated by the extra-corporeal circulation. In addition, NGAL synthesis is induced in epithelial cells in inflammatory and neoplastic colorectal diseases. In conclusion, NGAL may serve as a scavenger of bacterial products to function in the anti-inflammatory process.
Specificity:
Lipocalin-2 polyclonal antibody detects endogenous levels of Lipocalin-2 protein.
Alternative names:
NGAL, LCN2, 24p3, 25 kDa alpha 2 microglobulin related subunit of MMP9, 25 kDa alpha-2-microglobulin-related subunit of MMP-9, Alpha 2 microglobulin related protein, HGNC:6526, HNL, Lcn 2, Lcn2, Lipocalin-2, Migration stimulating factor inhibitor, MSFI, Neutrophil gelatinase associated lipocalin, Neutrophil gelatinase associated lipocalin precursor, Neutrophil gelatinase-associated lipocalin, NGAL, NGAL, Oncogene 24p3, Oncogenic lipocalin 24p3, p25, Siderocalin, siderocalin LCN2, SV40 induced 24P3 protein, Uterocalin,
Species reactivity:
Human
Host:
Rabbit
Ig type:
Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2
Immunogen:
recombinant protein
Purification & Purity:
ProA affinity purified
Molecular weight:
23 kDa
Applications:
WB ICC/IF IHC
Usage:
WB:1:1,000-1:5,000 ICC:1:100-1:500 IHC:1:50-1:200 FC:1:50-1:100
Storage:
Store at +4°C after thawing. Aliquot store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
Precautions:
For research use only, not for use in diagnostic procedure.
More info:
Email: info@sobekbio.com
Orders:
Email: orders@sobekbio.com
