Background:

LIN-28 is a highly conserved, RNA-binding, cytoplasmic protein. It consists of a cold shock domain and retroviral-type (CCHC) zinc finger motifs that were first identified in Caenorhabditis elegans. LIN-28 controls the timing of events during embryonic development and is readily expressed in embryos, embryonic stem cells and embryonal carcinoma cells. The presence of LIN-28 persists in some adult tissues including cardiac and skeletal muscle. In differentiating myoblasts, LIN-28 increases protein sysnthesis efficiency and binds to the growth and differentiation factor IGF-II.

Specificity:

Lin28 polyclonal antibody detects endogenous levels of Lin28 protein.

Alternative names:

Lin-28A, LIN28A, AL024421, CSDD1, CSDD2, FLJ12457, Lin 28, Lin 28 homolog (C. elegans), Lin 28 homolog A (C. elegans), Lin 28 homolog A, Lin 28 homolog, Lin-28A, Lin28, Lin28, C. elegans, homolog of, A, LIN28A, LN28A, Protein lin-28 homolog A, Protein lin-28 homolog B, RNA binding protein lin 28, Tex17, ZCCHC1, Zinc finger CCHC domain containing 1, Zinc finger CCHC domain containing protein 1, Zinc finger CCHC domain-containing protein 1,

Species reactivity:

Human

Host:

Rabbit

Ig type:

Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Immunogen:

recombinant protein

Purification & Purity:

ProA affinity purified

Molecular weight:

23 kDa

Applications:

WB IP FC

Usage:

WB:1:500-1:1,000 IP:1:10-1:50 FC:1:50-1:100

Storage:

Store at +4°C after thawing. Aliquot store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.

Precautions:

For research use only, not for use in diagnostic procedure.

More info:

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