Background:

This potassium channel is controlled by G proteins. Inward rectifier potassium channels are characterized by a greater tendency to allow potassium to flow into the cell rather than out of it. Their voltage dependence is regulated by the concentration of extracellular potassium; as external potassium is raised, the voltage range of the channel opening shifts to more positive voltages. The inward rectification is mainly due to the blockage of outward current by internal magnesium. Can be blocked by external barium.

Specificity:

Kir3.4 polyclonal antibody detects endogenous levels of Kir3.4 protein.

Alternative names:

GIRK-4, CIR, IRK-4, KCNJ5, GIRK4, Cardiac ATP sensitive potassium channel, Cardiac inward rectifier, CIR, G protein activated inward rectifier potassium channel 4, G protein-activated inward rectifier potassium channel 4, GIRK 4, GIRK-4, GIRK4, Heart KATP channel, Inward rectifier K(+) channel Kir3.4, Inward rectifier K+ channel KIR3.4, Inward rectifier potassium channel KIR3.4, inwardly rectifying subfamily J member 5, IRK-4, IRK5, KATP 1, KATP-1, KATP1, KCNJ 5, Kcnj5, KIR 3.4, KIR3.4, LQT13, Potassium channel, Potassium channel inwardly rectifying subfamily J member 5, Potassium inwardly rectifying channel J5, Potassium inwardly rectifying channel subfamily J member 5, potassium voltage-gated channel subfamily J member 5,

Species reactivity:

Human, Mouse, Rat

Host:

Rabbit

Ig type:

Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Immunogen:

Synthetic peptide within N-terminal human Kir3.4.

Purification & Purity:

Peptide affinity purified.

Molecular weight:

48 kDa

Applications:

WB ICC IHC FC

Usage:

WB:1:500 ICC:1:50-1:200 IHC:1:50-1:200 FC:1:50-1:100

Storage:

Store at +4°C after thawing. Aliquot store at -20°C. Avoid repeated freeze / thaw cycles.

Precautions:

For research use only, not for use in diagnostic procedure.

More info:

Email: info@sobekbio.com

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