Background:

Voltage-insensitive potassium channel (PubMed:22282805). Channel opening is triggered by mechanical forces that deform the membrane (PubMed:22282805, PubMed:25471887, PubMed:25500157). Channel opening is triggered by raising the intracellular pH to basic levels (By similarity). The channel is inactive at 24 degrees Celsius (in vitro); raising the temperature to 37 degrees Celsius increases the frequency of channel opening, with a further increase in channel activity when the temperature is raised to 42 degrees Celsius (By similarity). Plays a role in the perception of pain caused by heat (By similarity). Plays a role in the sensory perception of pain caused by pressure (By similarity).

Specificity:

K2P4.1 polyclonal antibody detects endogenous levels of K2P4.1 protein.

Alternative names:

TRAAK, Two pore K(+) channel KT4.1, KCNK4, TRAAK, K2p4.1, K2P4.1 potassium channel, KCNK 4, MGC144821, Potassium channel subfamily K member 4, Potassium inwardly rectifying channel subfamily K member 4, TRAAK, TRAAK1, TRAAKt, TWIK related arachidonic acid stimulated potassium channel protein, Two pore K(+) channel KT4.1, Two pore K+ channel KT4.1, Two pore potassium channel KT4.1,

Species reactivity:

Human, Mouse

Host:

Rabbit

Ig type:

Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Immunogen:

Synthetic peptide within human K2P4.1 aa 320-380.

Purification & Purity:

Peptide affinity purified.

Molecular weight:

43 kDa

Applications:

WB IHC FC

Usage:

WB:1:500 IHC:1:50-1:200 FC:1:50-1:100

Storage:

Store at +4°C after thawing. Aliquot store at -20°C. Avoid repeated freeze / thaw cycles.

Precautions:

For research use only, not for use in diagnostic procedure.

More info:

Email: info@sobekbio.com

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