Bioworld Technology

Bioworld Technology is manufacturer of over 15,000 highly purified Monoclonal and Polyclonal Antibodies, Peptides, Proteins, and other related Research Products. Their products are used in all biological fields. An important focus in research taking place today is in work investigating Signal transduction pathways, Cardiac markers, Neuroscience as well as Stem cell research. Bioworld Technology is committed to providing customers with innovative research tools and to helping scientists determine the mechanisms of cell function and disease.
Bioworld Technology is one of the leading phospho-antibody manufacturers. They have produced over 500 phospho-antibodies for AKT, AMPK, GSK, STAT pathways. The peptides corresponding to each phospho-antibody have also been listed to help scientists.
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Bioworld Technology continues to manufacture product lines to the highest standards; and all of their scientists are dedicated to the mystery of the world of science.

ITPR2 polyclonal antibody BS90745

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Specifications

size	50ul/100ul

Background:

The protein encoded by this gene belongs to the inositol 1,4,5-triphosphate receptor family, whose members are second messenger intracellular calcium release channels. These proteins mediate a rise in cytoplasmic calcium in response to receptor activated production of inositol triphosphate. Inositol triphosphate receptor-mediated signaling is involved in many processes including cell migration, cell division, smooth muscle contraction, and neuronal signaling. This protein is a type 2 receptor that consists of a cytoplasmic amino-terminus that binds inositol triphosphate, six membrane-spanning helices that contribute to the ion pore, and a short cytoplasmic carboxy-terminus. A mutation in this gene has been associated with anhidrosis, suggesting that intracellular calcium release mediated by this protein is required for eccrine sweat production.

Specificity:

ITPR2 polyclonal antibody detects endogenous levels of ITPR2 protein.

Alternative names:

IP3R 2, InsP3R2, Type 2 InsP3 receptor, ITPR2, 4, 5-trisphosphate receptor, Inositol 1 4 5 trisphosphate receptor type 2, Inositol 1, 4, 5-trisphosphate receptor type 2, Inositol 145 trisphosphate receptor type 2, InsP3 R2, InsP3R2, IP3 R2, IP3 receptor, IP3 receptor isoform 2, IP3R 2, IP3R2, ITPR 2, Itpr2, ITPR2, Type 2 inositol 1 4 5 trisphosphate receptor, Type 2 inositol 1, Type 2 inositol 145 trisphosphate receptor, Type 2 InsP3 receptor,

Species reactivity:

Human, Mouse, Rat

Host:

Rabbit

Ig type:

Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Immunogen:

Recombinant protein within human ITPR2 aa 1100-1450.

Purification & Purity:

Protein affinity purified.

Molecular weight:

308 kDa

Applications:

DotBlot ICC IHC FC

Usage:

DotBlot:1:2,000-1:5,000 ICC:1:50-1:100 IHC:1:50-1:200 FC:1:50-1:100

Storage:

Store at +4°C after thawing. Aliquot store at -20°C. Avoid repeated freeze / thaw cycles.

Precautions:

For research use only, not for use in diagnostic procedure.

More info:

Email: info@sobekbio.com

Orders:

Email: orders@sobekbio.com