Background:

Chemokines are members of a superfamily of inducible, secreted, pro-inflammatory cytokines. Members of the chemokine family exhibit 20% to 50% homology in their predicted amino acid sequences and are divided into four subfamilies: C-C, C-X-C, C and C-X3-C. In the C-X-C or α subfamily, the first two of four cysteine motifs are separated by another amino acid residue. In the second subfamily, designated C-C or β, the first cysteines are adjacent. C subfamily members, also designated γ chemokines, lack the first and third cysteine residues of the conserved motif. In the C-X3-C, or δ subfamily, members have three amino acids between the two cysteines. The C-X-C chemokine subfamily includes IL-8, GROα/β/γ (and the murine homologs KC, MIP-2α and MIP-2β), platelet basic protein, ENA-78, GCP-2, PF4, IP-10 (and its murine homolog, CRG) and MIG.

Specificity:

IP10 polyclonal antibody detects endogenous levels of IP10 protein.

Alternative names:

Gamma-IP10, IP-10, CXCL10, Interferon gamma induced factor MOB1, mouse, homolog of, Interferon gamma induced protein 10, 10 kDa interferon gamma induced protein, 10 kDa interferon gamma-induced protein, C X C motif chemokine 10, C7, Chemokine (C X C motif) ligand 10, Chemokine CXC motif ligand 10, Crg 2, CRG2, CXCL10, CXCL10(1-73), CXL10, Gamma IP10, Gamma-IP10, gIP 10, GIP10, IFI10, INP 10, INP10, Interferon activated gene 10, Interferon activated gene 10, Interferon gamma induced cell line, Interferon inducible cytokine IP 10, Interferon inducible cytokine IP10, IP 10, IP-10, Mob 1, MOB1, Protein 10 from interferon (gamma) induced cell line, SCYB10, Small inducible cytokine B10, Small inducible cytokine B10 precursor, Small inducible cytokine subfamily B (Cys X Cys) member 10, Small inducible cytokine subfamily B CXC member 10, Small inducible cytokine subfamily B, member 10, Small-inducible cytokine B10,

Species reactivity:

Human

Host:

Rabbit

Ig type:

Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Immunogen:

recombinant protein

Purification & Purity:

ProA affinity purified

Molecular weight:

10 kDa

Applications:

WB ICC/IF IHC

Usage:

WB:1:500-1:1,000 ICC:1:50-1:100 IHC:1:50-1:200

Storage:

Store at +4°C after thawing. Aliquot store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.

Precautions:

For research use only, not for use in diagnostic procedure.

More info:

Email: info@sobekbio.com

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