Background:

Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Could also have a single-stranded nucleic acid-binding activity and could play a role in RNA and/or DNA metabolism. It may also have a role in the development of malignancy and the growth progression of some tumors.

Specificity:

IMPDH2 polyclonal antibody detects endogenous levels of IMPDH2 protein.

Alternative names:

IMP dehydrogenase 2, IMPD 2, IMPDH 2, IMPDH2, IMPD2, IMDH2, IMP (inosine monophosphate) dehydrogenase 2, IMP dehydrogenase 2, IMP oxireductase 2, IMPD 2, IMPD2, IMPDH 2, IMPDH II, IMPDH-II, Impdh2, Inosine 5' monophosphate dehydrogenase 2, Inosine 5' phosphate dehydrogenase 2, Inosine monophosphate dehydrogenase type II, Inosine-5''-monophosphate dehydrogenase 2,

Species reactivity:

Human, Mouse, Rat

Host:

Rabbit

Ig type:

Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Immunogen:

Recombinant protein within C-terminal human IMPDH2.

Purification & Purity:

ProA affinity purified

Molecular weight:

56 kDa

Applications:

WB ICC IF IHC FC IP

Usage:

WB:1:500-1:2,000 ICC/IF:1:50-1:200 IHC:1:50-1:200 FC:1:10-1:50 IP:1:10-1:50

Storage:

Store at +4°C after thawing. Aliquot store at -20°C. Avoid repeated freeze / thaw cycles.

Precautions:

For research use only, not for use in diagnostic procedure.

More info:

Email: info@sobekbio.com

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