Background:

NF45 (ILF2, nuclear factor of activated T cells 45 kDa) is a transcription factor that interacts with NF90 (ILF3, DRBP76) to regulate gene expression. NF45 and NF90 are proteins that belong to the double-stranded RNA-binding protein family and both are substrates for the dsRNA-activated protein kinase, PKR. The NF45/NF90 heterodimer is mainly involved in regulating IL-2 expression by binding to the antigen receptor response element (ARRE) target sequence of the IL-2 enhancer. In neuronal cells, the NF45/NF90 heterodimer can repress human rhinovirus type 2 replication by binding to a 5' untranslated region of the viral RNA that encodes the internal ribosome entry site (IRES).

Specificity:

ILF2 polyclonal antibody detects endogenous levels of ILF2 protein.

Alternative names:

ILF2, NF45, PRO3063, HGNC:6037, ILF 2, ilf2, ILF2, Interleukin enhancer binding factor 2, Interleukin enhancer binding factor 2, 45kDa, Interleukin enhancer-binding factor 2, MGC8391, NF 45, NF45, Nuclear factor of activated T cells 45 kDa, Nuclear factor of activated T-cells 45 kDa, PRO3063,

Species reactivity:

Human, Mouse, Rat

Host:

Rabbit

Ig type:

Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Immunogen:

Recombinant protein

Purification & Purity:

ProA affinity purified

Molecular weight:

43 kDa

Applications:

WB IP IHC FC

Usage:

WB:1:500 IHC:1:50-1:200 FC:1:50-1:100 IP:1:10-1:20

Storage:

Store at +4°C after thawing. Aliquot store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.

Precautions:

For research use only, not for use in diagnostic procedure.

More info:

Email: info@sobekbio.com

Orders:

Email: orders@sobekbio.com