Background:

Cytokines are small, soluble proteins with pleiotropic effects on a variety of cell types. Cytokines have a regulatory function over the immune system and mediate aspects of inflammatory response. They exert their biological effects through the binding of membrane-bound receptors which, in turn, initiate signal transduction cascades and elicit physiological changes in their target cell. IL-17RB is a member of the cytokine receptor family and acts as a receptor for the proinflammatory cytokines IL-17B and IL-17E. It may play a role in hematopoietic cell differentiation and growth. IL-17RB expression is high in liver, colon, brain, kidney and testis. IL-17RB is detected in fibroblast-like synoviocytes of rheumatoid arthritis patients.

Specificity:

IL17RB polyclonal antibody detects endogenous levels of IL17RB protein.

Alternative names:

IL-17 receptor B, IL-17RB, IL-17Rh1, IL17Rh1, IL-17B receptor, IL17RB, CRL4, EVI27, IL17BR , UNQ2501/PRO19612, CRL 4, CRL4, Cytokine receptor CRL4, EVI 27, EVI27, IL 17 receptor B, IL 17 receptor homolog 1, IL 17B receptor, IL 17RB, IL 17Rh1, IL17BR, IL17RB, IL17RH1, Interleukin 17 receptor B, Interleukin 17 receptor homolog 1, Interleukin 17 receptor homolog, Interleukin 17B receptor, MGC5245,

Species reactivity:

Human, Mouse, Rat

Host:

Rabbit

Ig type:

Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Immunogen:

Recombinant protein

Purification & Purity:

ProA affinity purified

Molecular weight:

56 kDa

Applications:

WB

Usage:

WB:1:500-1:1,000

Storage:

Store at +4°C after thawing. Aliquot store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.

Precautions:

For research use only, not for use in diagnostic procedure.

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