Background:

The heat shock proteins (HSPs) comprise a group of highly conserved, abundantly expressed proteins with diverse functions, including the assembly and sequestering of multiprotein complexes, transportation of nascent polypeptide chains across cellular membranes and regulation of protein folding. Heat shock protein 75 mitochondrial precursor (HSP 75), also called tumor necrosis factor type 1 receptor-associated protein (TRAP1), is a 704 amino acid member of the heat shock protein 90 family. HSP 75 localizes to the mitochondrion and is expressed in a variety of tissues, including skeletal muscle, liver, heart, brain, pancreas, lung and placenta, functioning as a chaperone that expresses an ATPase activity.

Specificity:

HSP75 polyclonal antibody detects endogenous levels of HSP75 protein.

Alternative names:

HSP 75, TRAP-1, TRAP1, Heat Shock Protein 75, Heat shock protein 75 kDa, Heat shock protein 75 kDa mitochondrial, HSP 75, HSP90L, mitochondrial, TNF receptor associated protein 1, TNFR Associated Protein, TNFR-associated protein 1, TRAP-1, Trap1, TRAP1, Tumor Necrosis Factor Receptor Associated Protein 1, Tumor necrosis factor type 1 receptor associated protein, Tumor necrosis factor type 1 receptor-associated protein,

Species reactivity:

Human

Host:

Rabbit

Ig type:

Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Immunogen:

recombinant protein

Purification & Purity:

ProA affinity purified

Molecular weight:

75 kDa

Applications:

WB IP

Usage:

WB:1:1,000-1:2,000

Storage:

Store at +4°C after thawing. Aliquot store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.

Precautions:

For research use only, not for use in diagnostic procedure.

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