Background:

HNF-4 alpha is a transcription factor that binds DNA as a homodimer. HNF-4 alpha is important in liver, kidney, and intestinal development. It has also been intensely studied as one of a variety of genes responsible for diabetes mellitus. HNF-4 alpha has been shown in knock out mice to be essential for the morphogenic and functional differentiation of hepatocytes. HNF-4 alpha is a dominant regulator of epithelial phenotypes able to drive the mesenchymal-to-epithelial transition when expressed in fibroblasts.

Specificity:

HNF4α polyclonal antibody detects endogenous levels of HNF4α protein.

Alternative names:

HNF-4-alpha, TCF-14, HNF4A, FLJ39654, FRTS4, Hepatic nuclear factor 4 alpha, Hepatocyte nuclear factor 4 alpha, Hepatocyte nuclear factor 4, Hepatocyte nuclear factor 4-alpha, HNF 4 alpha, HNF 4, HNF-4-alpha, HNF4, HNF4A, HNF4A, HNF4a7, HNF4a8, HNF4a9, Hnf4alpha, HNF4alpha10/11/12, MODY 1, MODY, MODY1, NR2A1, NR2A21, Nuclear receptor subfamily 2 group A member 1, OTTHUMP00000031060, OTTHUMP00000031062, TCF 14, TCF, TCF-14, TCF14, Tcf4, Transcription factor 14, hepatic nuclear factor, Transcription factor 14, Transcription factor HNF 4, Transcription factor HNF-4, Transcription factor HNF4,

Species reactivity:

Human

Host:

Rabbit

Ig type:

Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Immunogen:

recombinant protein

Purification & Purity:

ProA affinity purified

Molecular weight:

53 kDa

Applications:

WB ICC/IF IHC FC

Usage:

WB:1:1,000 ICC:1:50-1:200 IHC:1:100-1:500 FC:1:50-1:100

Storage:

Store at +4°C after thawing. Aliquot store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.

Precautions:

For research use only, not for use in diagnostic procedure.

More info:

Email: info@sobekbio.com

Orders:

Email: orders@sobekbio.com