Background:

Major histocompatibility complex, class II, DQ alpha 1, also known as HLA-DQA1, is a human gene present on short arm of chromosome 6 (6p21.3) and also denotes the genetic locus which contains this gene. The protein encoded by this gene is one of two proteins that are required to form the DQ heterodimer, a cell surface receptor essential to the function of the immune system.HLA-DQA1 belongs to the HLA class II alpha chain paralogues. This class II molecule is a heterodimer consisting of an alpha (DQA) and a beta chain (DQB), both anchored in the membrane. It plays a central role in the immune system by presenting peptides derived from extracellular proteins. Class II molecules are expressed in antigen-presenting cells.

Specificity:

HLA-DQA1 polyclonal antibody detects endogenous levels of HLA-DQA1 protein.

Alternative names:

HLA class II histocompatibility antigen, DQ alpha 1 chain, DC-1 alpha chain, DC-alpha, HLA-DCA, MHC class II DQA1, CD, CELIAC1, DC 1 alpha chain, DC alpha, DC-1 alpha chain, DC-alpha, DC1, included, DQ alpha 1 chain, DQ-A1, DQ-DRW9 alpha chain, DQA1, FLJ27088, FLJ27328, Gluten-sensitive enteropathy (celiac disease), GSE, HLA class II histocompatibility antigen, HLA class II histocompatibility antigen, DQ alpha 1 chain, HLA class II histocompatibility antigen, DQ(W3) alpha chain, HLA-DCA, HLA-DQA, HLA-DQA1, HLA-DQA1 major histocompatibility complex, class II, DQ alpha 1, HLADC histocompatibility type, Immune response antigens HIa, included, leucocyte antigen DQA1, leukocyte antigen alpha chain, LOC100133678, LOC100507686, LOC100509457, Major histocompatibility complex, class II, DQ alpha 1, MGC149527, MHC class II antigen, MHC class II DQA1, MHC class II HLA-D alpha glycoprotein, MHC class II HLA-DQ alpha 1, MHC class II surface glycoprotein, MHC HLA-DQ alpha, OTTHUMP00000029141, OTTHUMP00000176885, OTTHUMP00000178551, OTTHUMP00000178552, OTTHUMP00000233817,

Species reactivity:

Human, Mouse, Rat

Host:

Rabbit

Ig type:

Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Immunogen:

Recombinant protein

Purification & Purity:

ProA affinity purified

Molecular weight:

28 kDa

Applications:

WB IHC IP

Usage:

WB:1:1,000-1:5,000 IHC:1:50-1:200 IP:1:10-1:50

Storage:

Store at +4°C after thawing. Aliquot store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.

Precautions:

For research use only, not for use in diagnostic procedure.

More info:

Email: info@sobekbio.com

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