Background:

Histone H1 protein binds to linker DNA between nucleosomes forming the macromolecular structure known as the chromatin fiber. Histones H1 are necessary for the condensation of nucleosome chains into higher-order structured fibers. Acts also as a regulator of individual gene transcription through chromatin remodeling, nucleosome spacing and DNA methylation.

Specificity:

Histone H1.2 polyclonal antibody detects endogenous levels of Histone H1.2 protein.

Alternative names:

HIST1H1C, H1F2, H1 histone family member 2, H1.a, H12, H1F2, H1s-1, HIST1H1C, Histone 1 H1c, Histone cluster 1 H1c, Histone H1.2, Histone H1c, Histone H1d, Histone H1s-1, MGC3992,

Species reactivity:

Human, Mouse, Rat

Host:

Rabbit

Ig type:

Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Immunogen:

Recombinant protein

Purification & Purity:

ProA affinity purified

Molecular weight:

29 kDa

Applications:

WB ICC IF IHC ChIP

Usage:

WB:1:500-1:2,000 ICC:1:50-1:100 IHC:1:50-1:200

Storage:

Store at +4°C after thawing. Aliquot store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.

Precautions:

For research use only, not for use in diagnostic procedure.

More info:

Email: info@sobekbio.com

Orders:

Email: orders@sobekbio.com