Background:

HE4 (whey acidic protein (WAP)-type four-disulfide core-2, WFDC2) is a small secretory protein that may influence sperm maturation. HE4 gene expression is high in pulmonary epithelial cells and in some ovarian cancers. HE4 protein has a WAP motif that contains eight cysteines forming four disulfide bonds at the core of the protein. The WAP motif functions as a protease inhibitor in many of the family members that contain them.

Specificity:

HE4 polyclonal antibody detects endogenous levels of HE4 protein.

Alternative names:

WFDC2, dJ461P17.6, EDDM4, epididymal protein 4, Epididymal secretory protein E4, Epididymis specific whey acidic protein type four disulfide core, HE 4, Major epididymis specific protein E4, Major epididymis-specific protein E4, MGC57529, Putative protease inhibitor WAP5, WAP 5, WAP domain containing protein HE4, WAP domain containing protein HE4 V4, WAP four disulfide core domain 2, WAP four disulfide core domain protein 2, WAP four-disulfide core domain protein 2, WAP5, WFDC 2, WFDC2, WFDC2,

Species reactivity:

Human, Mouse

Host:

Rabbit

Ig type:

Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Immunogen:

recombinant protein

Purification & Purity:

ProA affinity purified

Molecular weight:

23 kDa

Applications:

WB ICC/IF IHC IP FC

Usage:

WB:1:1,000-1:2,000 ICC:1:50-1:200 IHC:1:50-1:200 FC:1:50-1:100

Storage:

Store at +4°C after thawing. Aliquot store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.

Precautions:

For research use only, not for use in diagnostic procedure.

More info:

Email: info@sobekbio.com

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