GLUT2 polyclonal antibody BS90583
Specifications
| 50ul/100ul |
Background:
Glucose is fundamental to the metabolism of mammalian cells. Its passage across cell membranes is mediated by a family of transporters termed glucose transporters or Gluts. Glut1, Glut3 and Glut4 are high-affinity transporters, whereas Glut2 is a low-affinity transporter. In adipose and muscle tissue, insulin stimulates a rapid and dramatic increase in glucose uptake, which is largely due to the redistribution of the insulin-inducible glucose transporter Glut4. In response to insulin, Glut4 is quickly shuttled from an intracellular storage site to the plasma membrane, where it binds glucose. In contrast, the ubiquitously expressed glucose transporter Glut1 is constitutively targeted to the plasma membrane and shows a much less dramatic translocation in response to insulin. Glut2 expression is seen in pancreatic beta cells, hepatocytes and basolateral membranes of intestinal and epithelial cells, while the highest expression of Glut3 has been found in neuronal tissue.
Specificity:
GLUT2 polyclonal antibody detects endogenous levels of GLUT2 protein.
Alternative names:
GLUT-2, SLC2A2, liver, Glucose Transporter 2, Glucose Transporter GLUT2, Glucose transporter type 2, Glucose transporter type 2 liver, Glucose transporter, liver/islet, GLUT-2, GLUT2, GTR2, GTT2, SLC2A2, Solute carrier family 2 (facilitated glucose transporter) member 2, Solute carrier family 2 facilitated glucose transporter member 2, Solute carrier family 2, facilitated glucose transporter member 2,
Species reactivity:
Human
Host:
Rabbit
Ig type:
Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2
Immunogen:
recombinant protein
Purification & Purity:
ProA affinity purified
Molecular weight:
57 kDa
Applications:
WB IHC FC
Usage:
WB:1:500-1:1,000 FC:1:50-1:100 IHC:1:50-1:200
Storage:
Store at +4°C after thawing. Aliquot store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
Precautions:
For research use only, not for use in diagnostic procedure.
More info:
Email: info@sobekbio.com
Orders:
Email: orders@sobekbio.com