Background:

Galectins are a family of soluble b-galactoside-binding animal lectins that modulate cell-to-cell adhesion and cell-to-extracellular matrix (ECM) interactions and play a role in tumor progression, pre-mRNA splicing and apoptosis. Galectin-7, expressed mainly in stratified squamous epithelium, is activated by p53 and repressed by retinoic acid. It is a pro-apoptotic protein that functions intracellularly upstream of JNK activation and cytochrome c release. The galectin-7 gene maps to chromosome 19. Mainly expressed in stratified squamous epithelium.

Specificity:

Galectin 7 polyclonal antibody detects endogenous levels of Galectin 7 protein.

Alternative names:

Gal-7, LGALS7, PIG1, LGALS7B, Gal-7, GAL7, Galectin 7B, Galectin-7, HKL-14, Human keratinocyte lectin 14, Keratinocyte lectin 14, Lectin galactoside binding soluble 7, Lectin, galactoside binding, soluble, 7B, LEG7, LGALS7, LGALS7A, LGALS7B, P53 induced protein 1, p53-induced gene 1 protein, Pi7, PIG1, TP53I1,

Species reactivity:

Human

Host:

Rabbit

Ig type:

Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Immunogen:

Recombinant protein

Purification & Purity:

ProA affinity purified

Molecular weight:

15 kDa

Applications:

WB ICC IF IHC IP

Usage:

ICC:1:50-1:200 IHC:1:100-1:300 WB:1:500-1:1,000 IP:1:10-1:50

Storage:

Store at +4°C after thawing. Aliquot store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.

Precautions:

For research use only, not for use in diagnostic procedure.

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