Background:

The FOX family of transcription factors share a common DIUA binding domain termed a winged-helix or forkhead domain. Many FOX proteins play important roles in development, metabolism, cancer and aging. Development of the vertebrate gut is controlled by paracrine crosstalk between the endodermal epithelium and the associated splanchnic mesoderm. FOXF2 (forkhead box F2), also known as FKHL or FREAC2, is expressed in lung and placenta, and has been shown to transcriptionally activate several lung-specific genes. FOXF2 interacts with transcription factors TFIIB and TBP, and may be involved in regulating transcription in embryogenesis and pattern formation in multicellular organisms. FOXF2-deficient mice develop cleft palate and an abnormal tongue, which suggests that FOXF2 may be critical for palatogenesis.

Specificity:

FOXF2 polyclonal antibody detects endogenous levels of FOXF2 protein.

Alternative names:

FREAC-2, FOXF2, FKHL6, FREAC2, FKH L6, FKHL 6, FKHL6, Forkhead box F2, Forkhead box protein F2, Forkhead like 6, Forkhead related activator 2, Forkhead related protein FKHL6, Forkhead related transcription factor 2, Forkhead, Drosophila, homolog-like 6, FOX F2, FOXF 2, FREAC 2, FREAC2, OTTHUMP00000017863,

Species reactivity:

Human, Mouse

Host:

Rabbit

Ig type:

Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Immunogen:

Peptide

Purification & Purity:

Peptide affinity purified

Molecular weight:

46 kDa

Applications:

WB

Usage:

WB:1:500

Storage:

Store at +4°C after thawing. Aliquot store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.

Precautions:

For research use only, not for use in diagnostic procedure.

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