Background:

Fatty acid-binding proteins, designated FABPs, are a family of homologous, cytoplasmic proteins that are expressed in a highly tissue-specific manner and play an integral role in the balance between lipid and carbohydrate metabolism. FABPs mediate fatty acid (FA) and/or hydrophobic ligand uptake, transport, and targeting within their respective tissues. The mechanisms underlying these actions can give rise to both passive diffusional uptake and protein-mediated transmembrane transport of FAs. FABPs are expressed in adipocytes (A-FABP), brain (B-FABP), epidermis (E-FABP, also designated psoriasis-associated FABP or PA-FABP), muscle and heart (H-FABP, also designated mammary-derived growth inhibitor or MDGI), intestine (I-FABP), liver (L-FABP), myelin (M-FABP) and testis (T-FABP). The human A-FABP gene is organized into 4 exons, maps to chromosome 8q21, and encodes a 132-amino acid protein. A-FABP protein comprises approximately 1% of the total cytosolic protein in human adipose tissue.

Specificity:

FABP4 polyclonal antibody detects endogenous levels of FABP4 protein.

Alternative names:

ALBP, A-FABP, AFABP, FABP4, 3T3-L1 lipid-binding protein, 422/aP2, A-FABP, adipocyte, Adipocyte lipid binding protein, Adipocyte lipid-binding protein, Adipocyte protein AP2, Adipocyte-type fatty acid-binding protein, AFABP, ALBP, ALBP/Ap2, aP2, Epididymis secretory protein Li 104, FABP, FABP4, FABP4, Fatty acid binding protein 4 adipocyte, Fatty acid binding protein 4, Fatty acid binding protein adipocyte, Fatty acid-binding protein 4, Fatty acid-binding protein, HEL S 104, Lbpl, Myelin P2 protein homolog, P15, P2 adipocyte protein, Protein 422,

Species reactivity:

Human, Mouse, Rat

Host:

Rabbit

Ig type:

Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Immunogen:

recombinant protein

Purification & Purity:

ProA affinity purified

Molecular weight:

15 kDa

Applications:

WB ICC/IF IHC

Usage:

WB:1:500-1:2,000 ICC:1:100-1:500 IHC:1:50-1:200

Storage:

Store at +4°C after thawing. Aliquot store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.

Precautions:

For research use only, not for use in diagnostic procedure.

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