Background:

Ezrin, Moesin and Radixin belong to a family of highly homologous Actinassociated proteins that are localized just beneath the plasma membrane. The proteins are believed to be involved in the mediation of interactions between cytoskeletal and membrane proteins. Ezrin serves as a major cytoplasmic substrate of various protein-tyrosine kinases, including the epidermal growth factor receptor. Ezrin has also been identified as a cAMP-dependent protein kinase (A-kinase) anchoring protein and designated AKAP78. Moesin and Radixin share over 70% homology with Ezrin and are coexpressed within various cell types. Despite the high degree of homology, the three proteins exhibit a distinct receptor-specific pattern of phosphorylation.

Specificity:

Ezrin polyclonal antibody detects endogenous levels of Ezrin protein.

Alternative names:

EZR, Villin 2 ezrin, CVIL, CVL, Cytovillin 2, Cytovillin, DKFZp762H157, Epididymis secretory protein Li 105, EZR, EZRI, Ezrin, FLJ26216, HEL S 105, MGC1584, p81, VIL 2, VIL2, Villin 2 (ezrin), Villin 2, Villin-2, Villin2,

Species reactivity:

Human

Host:

Rabbit

Ig type:

Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Immunogen:

recombinant protein

Purification & Purity:

ProA affinity purified

Molecular weight:

80 kDa

Applications:

WB IHC

Usage:

WB:1:500-1:1,000 IHC:1:50-1:200

Storage:

Store at +4°C after thawing. Aliquot store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.

Precautions:

For research use only, not for use in diagnostic procedure.

More info:

Email: info@sobekbio.com

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