Background:

The karyopherin-related nuclear transport factor Exportin 5, also known as Exp5, preferentially recognizes and transports RNAs containing minihelix motifs, structural cis-acting export elements that comprise a double-stranded stem (14 nucleotides) with a base-paired 5' end and a 3-8-nucleotide protruding 3' end. Exportin 5 also mediates protein transport between the nuclear and cytoplasmic compartment. Exportin 5 belongs to a large family of karyopherins and stimulates nuclear export of dsRNA binding proteins eEF1A and tRNA.

Specificity:

Exportin-5 polyclonal antibody detects endogenous levels of Exportin-5 protein.

Alternative names:

Exp5, XPO5, KIAA1291, RANBP21, Exp 5, Exp5, Exportin 5, Exportin-5, Exportin5, FLJ14239, FLJ32057, FLJ45606, KIAA1291, OTTHUMP00000016472, Ran binding protein 21, Ran-binding protein 21, Ranbp 21, Ranbp21, Xpo 5, xpo5, XPO5,

Species reactivity:

Human, Mouse, Rat

Host:

Rabbit

Ig type:

Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Immunogen:

Recombinant protein within human Exportin-5 aa 1-200.

Purification & Purity:

ProA affinity purified

Molecular weight:

136 kDa

Applications:

WB IHC FC ICC/IF

Usage:

WB:1:500-1:2,000 IHC:1:100-1:400 FC:1:50-1:100 ICC/IF:1:100

Storage:

Store at +4°C after thawing. Aliquot store at -20°C. Avoid repeated freeze / thaw cycles.

Precautions:

For research use only, not for use in diagnostic procedure.

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