Background:

DDAH, a dimethylarginine dimethylaminohydrolase, hydrolyzes dimethyl arginine (ADMA) and monomethyl arginine (MMA), both inhibitors of nitric oxide synthases, and may be involved in in-vivo modulation of nitric oxide production. Impairment of DDAH causes ADMA accumulation and a reduction in cGMP generation. DDAH II, the predominant DDAH isoform in endothelial cells, facilitates the induction of nitric oxide synthesis by all-trans-Retinoic acid (atRA). DDAH proteins are highly expressed in colon, kidney, stomach and liver tissues.

Specificity:

DDAH2 polyclonal antibody detects endogenous levels of DDAH2 protein.

Alternative names:

DDAH-2, Dimethylarginine dimethylaminohydrolase 2, DDAH2, DDAH, G6A, NG30, DDAH, DDAH II, DDAH-2, DDAH2, DDAH2, DDAHII, Dimethylargininase 2, Dimethylargininase-2, Dimethylarginine dimethylaminohydrolase 2, Dimethylarginine dimethylaminohydrolase II, G6a, N(G), N(G)-dimethylarginine dimethylaminohydrolase 2, NG dimethylarginine dimethylamino hydrolase homolog, NG30, OTTHUMP00000029307, OTTHUMP00000029310, OTTHUMP00000174488, OTTHUMP00000174489, Protein G6a, S phase protein, S-phase protein,

Species reactivity:

Human, Mouse, Rat

Host:

Rabbit

Ig type:

Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Immunogen:

Synthetic peptide within Human DDAH2 aa 1-100

Purification & Purity:

ProA affinity purified

Molecular weight:

30kDa

Applications:

WB IP

Usage:

WB:1:2,000-1:5,000 IP:1:10-:50

Storage:

Store at +4°C after thawing. Aliquot store at -20°C. Avoid repeated freeze / thaw cycles.

Precautions:

For research use only, not for use in diagnostic procedure.

More info:

Email: info@sobekbio.com

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