Background:

DAZL (deleted in azoospermia-like), an RNA-binding protein that effects spermatogenesis, is an autosomal homolog of the Y chromosome DAZ (deleted in azoospermia). The gene encoding human DAZL maps to chromosome locus 3p24. DAZL, like other members of The DAZ family members are included in germ cells in both male and female gonads. A Thr 54-to-Ala mutation within the RNA-recognition domain of DAZL proteins contributes to spermatogenic failure. Infertility in DAZL knockout catisatalities are unable to complete the first meiotic prophase in the first wave of spermatogenesis.

Specificity:

DAZL polyclonal antibody detects endogenous levels of DAZL protein.

Alternative names:

DAZL, DAZH, DAZL1, DAZLA, SPGYLA, DAZ homolog, DAZ like autosomal, DAZ-like autosomal, DAZH, DAZL 1, DAZL, DAZL, DAZL1, DAZLA, Deleted in azoospermia like 1, Deleted in azoospermia like, Deleted in azoospermia like autosomal, Deleted in azoospermia-like 1, Deleted in azoospermia-like, Germline specific RNA binding protein, MGC26406, Spermatogenesis gene on the Y like autosomal, SPGY like autosomal, SPGY-like-autosomal, SPGYLA, Tpx2,

Species reactivity:

Human, Mouse, Rat

Host:

Rabbit

Ig type:

Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Immunogen:

recombinant protein

Purification & Purity:

ProA affinity purified

Molecular weight:

33 kDa

Applications:

WB IHC

Usage:

WB:1:500 IHC:1:50

Storage:

Store at +4°C after thawing. Aliquot store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.

Precautions:

For research use only, not for use in diagnostic procedure.

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