Background:

Connective tissue growth factor (CTGF, also known as hypertrophic chondrocyte-specific gene product 24 or Hcs24), is a member of the CCN family of immediate early proteins, which are involved in cell proliferation, migration and matrix production. CTGF is a cysteine-rich peptide that is secreted by endothelial cells, fibroblasts, smooth muscle cells and myofibroblasts. Its expression is increased in various human and animal fibrotic diseases. Specifically, CTGF has been observed to be strongly upregulated in human proliferative and fibrogenic renal disease. In addition, CTGF is a growth factor for vascular smooth muscle cells (VSMC) and may play a similar role in promoting VSMC growth and migration in vitro.

Specificity:

CTGF polyclonal antibody detects endogenous levels of CTGF protein.

Alternative names:

IBP-8, IGF-binding protein 8, IGFBP-8, CTGF, CCN2, HCS24, IGFBP8, CCN 2, CCN family member 2, CCN2, Connective tissue growth factor, Ctgf, CTGF, Hcs 24, Hcs24, Hypertrophic chondrocyte specific protein 24, Hypertrophic chondrocyte-specific gene product 24, Hypertrophic chondrocyte-specific protein 24 antibody IBP-8, IGF-binding protein 8, IGFBP-8, IGFBP8, Insulin like Growth Factor Binding Protein 8, Insulin-like growth factor-binding protein 8, MGC102839, NOV 2, NOV2,

Species reactivity:

Human, Mouse

Host:

Rabbit

Ig type:

Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Immunogen:

Recombinant protein with human CTGF aa 150-300.

Purification & Purity:

Protein affinity purified.

Molecular weight:

38 kDa

Applications:

WB ICC IHC

Usage:

WB:1:500 ICC:1:50-1:200 IHC:1:50-1:200

Storage:

Store at +4°C after thawing. Aliquot store at -20°C. Avoid repeated freeze / thaw cycles.

Precautions:

For research use only, not for use in diagnostic procedure.

More info:

Email: info@sobekbio.com

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