Background:

Collapsin response mediator proteins (CRMPs), including CRMP-1 (DRP-1), CRMP-2 (DRP-2 or TOAD64), CRMP-3 (DRP-4), CRMP-4 (DRP-3) and CRMP-5 (DRP-5), mediate signal transduction after exposure of neural cells to the axon guidance molecule Semaphorin 3A (SEMA3A)/collapsin. CRMPs are present in the developing cerebral cortex and neocortical neurons and are responsive to SEMA3A. In the adult brain, the expression of CRMPs is dramatically downregulated. However, they remain expressed in structures that retain their capacity for differentiation and plasticity. CRMP-1 is also involved in cancer invasion and metastasis.

Specificity:

CRMP1 polyclonal antibody detects endogenous levels of CRMP1 protein.

Alternative names:

CRMP-1, ULIP-3, CRMP1, DPYSL1, ULIP3, Collapsin response mediator protein 1, CRMP 1, CRMP-1, Crmp1, Dihydropyrimidinase like 1, Dihydropyrimidinase related protein 1, Dihydropyrimidinase-related protein 1, DPYL1, DPYSL1, DRP 1, DRP-1, DRP1, ULIP-3, Ulip3, Unc-33-like phosphoprotein 3,

Species reactivity:

Human, Mouse, Rat

Host:

Rabbit

Ig type:

Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Immunogen:

Recombinant protein

Purification & Purity:

ProA affinity purified

Molecular weight:

74/62 kDa

Applications:

WB ICC IHC FC IP

Usage:

WB:1:500-1:2,000 ICC:1:50-1:200 IHC:1:50-1:200 FC:1:50-1:100

Storage:

Store at +4°C after thawing. Aliquot store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.

Precautions:

For research use only, not for use in diagnostic procedure.

More info:

Email: info@sobekbio.com

Orders:

Email: orders@sobekbio.com