Background:

Clathrin is a major cytosolic coat protein in pits and vesicles originating from the plasma membrane and the trans-Golgi network. In receptor-mediated endocytosis, receptor proteins are englufed by clathrin-coated vesicles. Clathrin is composed of three heavy chains and three light chains which associate non-covalently to form a triskelion structure. Clathrin heavy chain (HC) is composed of a terminal globular domain, a distal segment and a proximal segment containing a light chain binding site. The proximal segment of the Clathrin HC protein is essential for interactions between clathrin heavy chains and light chains which result in the formation of the triskelion structure.

Specificity:

CLTCL1 polyclonal antibody detects endogenous levels of CLTCL1 protein.

Alternative names:

CLH-22, CLTCL1, CLH22, CLTCL, CLTD, CHC17, Clathrin heavy chain, Clathrin heavy chain 1, Clathrin heavy chain 2, Clathrin heavy chain like 1, Clathrin heavy chain on chromosome 17, Clathrin heavy polypeptide, CLH 17, CLH 22, CLH-17, CLH1, CLH17, CLH22, CLTC, CLTCL, CLTCL1, CLTCL2, CLTD, Hc, KIAA0034,

Species reactivity:

Human, Mouse,Rat

Host:

Rabbit

Ig type:

Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Immunogen:

recombinant protein

Purification & Purity:

ProA affinity purified

Molecular weight:

191/187 kDa

Applications:

WB IHC

Usage:

WB:1:500-1:2,000 IHC:1:50-1:200

Storage:

Store at +4°C after thawing. Aliquot store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.

Precautions:

For research use only, not for use in diagnostic procedure.

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