Background:

Chromogranin A is a member of the chromogranin/secretogranin family of neuroendocrine secretory proteins. It is located in secretory vesicles of neurons and endocrine cells. Chromogranin A is the precursor to several functional peptides including vasostatin, pancreastatin, catestatin and parastatin. These peptides negatively modulate the neuroendocrine function of the releasing cell (autocrine) or nearby cells (paracrine). Chromogranin A might promote the generation of secretory granules. It is used as an indicator for pancreas and prostate cancer. It might play a role in early neoplasic progression. It is also elevated in diabetes.

Specificity:

Chromogranin A polyclonal antibody detects endogenous levels of Chromogranin A protein.

Alternative names:

CgA, CISY, Citrate synthase, Citrate synthase, mitochondrial, citrate synthetase, Cs, EC 2.3.3, EC 2.3.3.1,

Species reactivity:

Human, mouse, rat

Host:

Rabbit

Ig type:

Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Immunogen:

peptide

Purification & Purity:

Peptide affinity purified

Molecular weight:

86 kDa

Applications:

WB IHC FC

Usage:

WB:1:2,000 IHC:1:200 FC:1:100-1:200

Storage:

Store at +4°C after thawing. Aliquot store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.

Precautions:

For research use only, not for use in diagnostic procedure.

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Email: info@sobekbio.com

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