CD79a polyclonal antibody BS90259
Specifications
| 50ul/100ul |
Background:
The mb-1 gene codes for a phosphoprotein, designated CD79a, that, together with the related CD79b protein, forms a dimer associated with membrane-bound immunoglobulin in B-cells. The CD79a/CD79b dimer is closely associated with the B-cell antigen receptor, in a similar manner to the association of CD3 with the T-cell receptor, and enables the cell to respond to the presence of antigens on its surface. The CD79a protein is present on the surface of B-cells throughout their life cycle, and is absent on all other healthy cells, making it a highly reliable marker for B-cells in immunohistochemistry. The B lymphocyte antigen receptor is a multimeric complex that includes the antigen-specific component, surface immunoglobulin (Ig). Surface Ig non-covalently associates with two other proteins, Ig-alpha and Ig-beta, which are necessary for expression and function of the B-cell antigen receptor. This gene encodes the Ig-alpha protein of the B-cell antigen component. Alternatively spliced transcript variants encoding different isoforms have been described.
Specificity:
CD79a polyclonal antibody detects endogenous levels of CD79a protein.
Alternative names:
CD79a, CD79A, IGA, MB1, B lymphocyte-specific MB1 protein, B-cell antigen receptor complex-associated protein alpha chain, CD 79a, CD79a, CD79a antigen (immunoglobulin-associated alpha), CD79A antigen, CD79a molecule, immunoglobulin-associated alpha, CD79A, Ig alpha, Ig-alpha, IGA, IgM-alpha, Immunoglobulin-associated alpha, Ly54, MB-1 membrane glycoprotein, MB1, Membrane-bound immunoglobulin-associated protein, Surface IgM-associated protein antibody
Species reactivity:
Human
Host:
Rabbit
Ig type:
Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2
Immunogen:
Recombinant protein within human CD79a aa 33-143.
Purification & Purity:
Protein A purified.
Molecular weight:
38 kDa, predicted molecular weight 25 kDa.
Applications:
WB IF IHC FC
Usage:
WB:1:500-1:1,000 IHC:1:50-1:200 IF:1:50-1:100 FC:1:50-1:100
Storage:
Store at +4℃ after thawing. Aliquot store at -20℃. Avoid repeated freeze / thaw cycles.
Precautions:
For research use only, not for use in diagnostic procedure.
More info:
Email: info@sobekbio.com
Orders:
Email: orders@sobekbio.com
