Background:

CD68, also called Scavenger Receptor D1 (SR-D1) or macrosialin in mouse, is a 110 kDa type I transmembrane glycoprotein that belongs to the LAMP family of molecules. It contains a 300 amino acid (aa) extracellular region that is rich in threonine and serine, a likely attachment site for multiple carbohydrates. Human CD68 shares 74% aa sequence identity to mouse CD68 in the extracellular region. CD68 is found on monocytes and macrophages and serves as a scavenger receptor for oxidized LDL.

Specificity:

CD68 polyclonal antibody detects endogenous levels of CD68 protein.

Alternative names:

CD68, CD 68, CD68, CD68 antigen, CD68 molecule, CD68, DKFZp686M18236, gp11, Gp110, LAMP4, Macrophage antigen CD68 (microsialin), MACROPHAGE ANTIGEN CD68, Macrosialin, SCARD1, Scavenger receptor class D member 1,

Species reactivity:

Human, Mouse, Rat

Host:

Rabbit

Ig type:

Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Immunogen:

recombinant protein

Purification & Purity:

ProA affinity purified

Molecular weight:

37 kDa

Applications:

WB

Usage:

WB:1:1,000

Storage:

Store at +4°C after thawing. Aliquot store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.

Precautions:

For research use only, not for use in diagnostic procedure.

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