Background:

This gene encodes a member of the Armadillo protein family, which function in adhesion between cells and signal transduction. Multiple translation initiation codons and alternative splicing result in many different isoforms being translated. Not all of the full-length natures of the described transcript variants have been determined. Read-through transcription also exists between this gene and the neighboring upstream thioredoxin-related transmembrane protein 2 (TMX2) gene. Binds to and inhibits the transcriptional repressor ZBTB33, which may lead to activation of target genes of the Wnt signaling pathway (By similarity). Associates with and regulates the cell adhesion properties of both C-, E- and N-cadherins, being critical for their surface stability. Implicated both in cell transformation by SRC and in ligand-induced receptor signaling through the EGF, PDGF, CSF-1 and ERBB2 receptors. Promotes GLIS2 C-terminal cleavage.

Specificity:

Catenin δ1 polyclonal antibody detects endogenous levels of Catenin δ1 protein.

Alternative names:

CAS, p120(ctn), CTNND1, KIAA0384, Cadherin associated Src substrate, Cadherin-associated Src substrate, CAS, Catenin (cadherin associated protein) delta 1, Catenin delta 1, Catenin delta, Catenin delta-1, CTND1, CTNND 1, CTNND, CTNND1, delta 1 Catenin, KIAA0384, p120, P120 CAS, p120 catenin, P120 CTN, p120(cas), p120(ctn), P120CAS, P120CTN antibody

Species reactivity:

Human, Rat

Host:

Rabbit

Ig type:

Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Immunogen:

Recombinant protein within human delta 1 Catenin/CAS aa 130-320.

Purification & Purity:

Protein A purified.

Molecular weight:

108 kDa

Applications:

WB ICC

Usage:

WB:1:500 ICC:1:50-1:200

Storage:

Store at +4℃ after thawing. Aliquot store at -20℃. Avoid repeated freeze / thaw cycles.

Precautions:

For research use only, not for use in diagnostic procedure.

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