Background:

The bromodomain-containing proteins include BRD2, BRD3, BRD4 and BRDT. BRD2 (RING3 protein) is a mitogen-activated nuclear protein whose gene is located in the human MHC II region, suggesting its relation to HLA-associated diseases. The gene encoding BRD3 (RING3-like protein) contains two bromodomains and maps to chromosome 9q34. BRD4 (HUNK1 protein) is a nuclear protein involved in the regulation of chromosomal dynamics during mitosis. The testis-specific bromodomain protein BRDT contains a PEST sequence, indicating that it undergoes rapid intracellular degradation. The bromodomain-containing proteins are ubiquitously expressed.

Specificity:

BRD2 polyclonal antibody detects endogenous levels of BRD2 protein.

Alternative names:

BRD2, KIAA9001, RING3, BRD 2, Brd2, BRD2, Bromodomain containing 2, Bromodomain-containing protein 2, D6S113E, DKFZp686N0336, Female sterile homeotic related gene 1, Female sterile homeotic related gene 1, mouse, homolog of, FLJ31942, FSH, FSRG1, KIAA9001, NAT, O27.1.1, Really interesting new gene 3 protein, RING3, RING3 PROTEIN, RNF3,

Species reactivity:

Human

Host:

Rabbit

Ig type:

Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Immunogen:

Recombinant protein within human BRD2 aa 1-200.

Purification & Purity:

ProA affinity purified

Molecular weight:

Predicted band size 88 kDa

Applications:

WB ICC IHC FC

Usage:

WB:1:500-1:2,000 ICC:1:50-1:200 IHC:1:50-1:200 FC:1:50-1:100

Storage:

Store at +4°C after thawing. Aliquot store at -20°C. Avoid repeated freeze / thaw cycles.

Precautions:

For research use only, not for use in diagnostic procedure.

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