Background:

Key regulator of striated muscle performance by acting as the major Ca2+ ATPase responsible for the reuptake of cytosolic Ca2+ into the sarcoplasmic reticulum. Catalyzes the hydrolysis of ATP coupled with the translocation of calcium from the cytosol to the sarcoplasmic reticulum lumen. Contributes to calcium sequestration involved in muscular excitation/contraction.

Specificity:

ATP2A1 polyclonal antibody detects endogenous levels of ATP2A1 protein.

Alternative names:

SERCA1, SR Ca(2+)-ATPase 1, ATP2A1, fast twitch skeletal muscle isoform, AT2A1, ATP2A, ATP2A1, ATPase Ca++ transporting cardiac muscle fast twitch 1, ATPase Ca++ transporting fast twitch 1, ATPase, Ca(2+)-transporting fast twitch 1, Calcium pump 1, Calcium transporting ATPase sarcoplasmic reticulum type fast twitch skeletal muscle isoform, Calcium-transporting ATPase sarcoplasmic reticulum type, EC 3.6.3.8, Endoplasmic reticulum class 1/2 Ca(2+) ATPase, Fast skeletal muscle SR calcium ATPase, OTTHUMP00000162561, OTTHUMP00000162562, Sarcoendoplasmic reticulum calcium ATPase, Sarcoplasmic reticulum Ca(2+)-ATPase 1, Sarcoplasmic/endoplasmic reticulum calcium ATPase 1, SERCA 1, SERCA1, SERCA1 truncated isoform, included, SR Ca(2+) ATPase 1, SR Ca(2+)-ATPase 1,

Species reactivity:

Human, Mouse, Rat

Host:

Rabbit

Ig type:

Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Immunogen:

Synthetis peptide within rat ATP2A1 aa 20-50.

Purification & Purity:

Peptide affinity purified.

Molecular weight:

110 kDa

Applications:

WB IHC FC

Usage:

WB:1:500-1:1,000 IHC:1:50-1:200 FC:1:50-1:100

Storage:

Store at +4°C after thawing. Aliquot store at -20°C. Avoid repeated freeze / thaw cycles.

Precautions:

For research use only, not for use in diagnostic procedure.

More info:

Email: info@sobekbio.com

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