Background:

Autophagy, a process that results in the lysosomal-dependent degradation of cytosolic compartments, is carried out by the autophagosome, which is a double-membrane vesicle whose formation is catalyzed by several autophagy-related gene (Atg) proteins. Atg9a (autophagy-related protein 9A), also known as APG9-like 1, is a 839 amino acid, multi-pass membrane protein that localizes to the pre-autophagosomal structure (PAS). Isolation membranes are suggested to originate from the PAS, enwrapping cytoplasmic components to form a double membrane autophagosome, which then fuses with the vacuole. Ubiquitously expressed in human adult tissues, Atg9a cycles between the Golgi and endosomes and, with the autophagosome-specific marker LC3, plays a critical role in starvation-induced autophagosome formation. Three isoforms of Atg9a exist as a result of alternative splicing events.

Specificity:

ATG9A polyclonal antibody detects endogenous levels of ATG9A protein.

Alternative names:

ATG9A, APG9 autophagy 9-like 1, APG9 like 1, APG9-like 1, APG9L1, ATG9, ATG9 autophagy related 9 homolog A, ATG9 autophagy related 9 homolog A (S. cerevisiae), ATG9A, ATG9A, Autophagy 9-like 1 protein, Autophagy related protein 9A, Autophagy-related protein 9A, mATG9, MGD3208, OTTHUMP00000206046, OTTHUMP00000206048, OTTHUMP00000206049, OTTHUMP00000206062,

Species reactivity:

Human, Mouse, Rat

Host:

Rabbit

Ig type:

Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Immunogen:

recombinant protein

Purification & Purity:

ProA affinity purified

Molecular weight:

94 kDa

Applications:

WB ICC IHC IP

Usage:

WB:1:1,000 ICC:1:50-1:200 IHC:1:50-1:200

Storage:

Store at +4°C after thawing. Aliquot store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.

Precautions:

For research use only, not for use in diagnostic procedure.

More info:

Email: info@sobekbio.com

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