Background:

Natriuretic peptides comprise a family of 3 structurally related molecules: atrial natriuretic peptide (ANP), brain natriuretic peptide (BNP), and C-type natriuretic peptide (CNP). ANP and BNP act mainly as cardiac hormones, produced primarily by the atrium and ventricle, respectively, while the gene encoding C-type natriuretic peptide is expressed mainly in the brain. These peptides possess potent natriuretic, diuretic, and vasodilating activities and are implicated in body fluid homeostasis and blood pressure control. ANP, BNP, and CNP are highly homologous within the 17-residue ring structure formed by an intramolecular disulfide linkage. The genes which encode for ANP and BNP map to human chromosome 1p36.2. The gene which encodes for CNP maps to human chromosome 2q24-qter.

Specificity:

ANP polyclonal antibody detects endogenous levels of ANP protein.

Alternative names:

CDD, CDP, ANF, ANP, NPPA, PND, ANF, ANF, ANP, ATFB6, Atrial natriuretic factor, Atrial natriuretic peptide, Atriopeptin, Cardiodilatin, Cardiodilatin-related peptide, Cardionatrin, CDD ANF, CDD, CDD-ANF, CDP, Natriuretic peptide A, Natriuretic peptide precursor A, NPPA, PND, Prepronatriodilatin,

Species reactivity:

Human

Host:

Rabbit

Ig type:

Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Immunogen:

Recombinant protein

Purification & Purity:

ProA affinity purified

Molecular weight:

16 kDa

Applications:

WB IP

Usage:

WB:1:500-1:2,000

Storage:

Store at +4°C after thawing. Aliquot store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.

Precautions:

For research use only, not for use in diagnostic procedure.

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