Background:

Fructose 1,6-bisphosphate aldolase catalyses the reversible condensation of glycerone-P and glyceraldehyde 3-phosphate into fructose 1,6-bisphosphate. Fructose 1,6-bisphosphate aldolase exists as three forms: the muscle-specific Aldolase A; the liver-specific Aldolase B; and the brain-specific Aldolase C. Aldolase A, B and C arose from a common ancestral gene from which Aldo-lase B first diverged. Aldolase A is one of the most highly-conserved enzymes known, with only about 2% of the residues changing per 100 million years. Aldolase B is regulated by the hormones insulin and glucagon, and has been implicated in hereditary fructose intolerance disease. Aldolase C is a polypeptide that is exclusively expressed in Purkinje cells. Aldolase C-positive Purkinje cells are organized in the cerebellum as stripes or bands that run from anterior to posterior across the cerebellum and alternate with bands of Aldolase C-negative Purkinje cells.

Specificity:

Aldolase polyclonal antibody detects endogenous levels of Aldolase protein.

Alternative names:

ALDOA, ALDA, ALDA, Aldo1, ALDOA, ALDOA, Aldolase 1, Aldolase A, Aldolase A fructose bisphosphatase, Aldolase A fructose bisphosphate, Aldolase, fructose-bisphosphate A, Epididymis secretory sperm binding protein Li 87p, FRUCTOALDOLASE A, Fructose 1 6 bisphosphate triosephosphate lyase, Fructose bisphosphate aldolase A, Fructose bisphosphate aldolase, FRUCTOSE-1, 6-BISPHOSPHATE ALDOLASE A, Fructose-bisphosphate aldolase A, Fructose-bisphosphate aldolase A Muscle-type, GSD12, HEL S 87p, Lung cancer antigen NY LU 1, Lung cancer antigen NY-LU-1, MGC10942, MGC17716, MGC17767, Muscle type aldolase, Muscle-type aldolase, RNALDOG5,

Species reactivity:

Human, Mouse, Rat, Zebrafish

Host:

Rabbit

Ig type:

Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Immunogen:

Recombinant protein

Purification & Purity:

ProA affinity purified

Molecular weight:

39 kDa

Applications:

WB ICC IF IHC

Usage:

WB:1:500-1:2,000 ICC/IF:1:50-1:200 IHC:1:50-1:200

Storage:

Store at +4°C after thawing. Aliquot store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.

Precautions:

For research use only, not for use in diagnostic procedure.

More info:

Email: info@sobekbio.com

Orders:

Email: orders@sobekbio.com