Background:

10-formyltetrahydrofolate dehydrogenase is an enzyme that in humans is encoded by the ALDH1L1 gene. The protein encoded by this gene catalyzes the conversion of 10-formyltetrahydrofolate, NADP, and water to tetrahydrofolate, NADPH, and carbon dioxide. The encoded protein belongs to the aldehyde dehydrogenase family and is responsible for formate oxidation in vivo. Deficiencies in this gene can result in an accumulation of formate and subsequent methanol poisoning.

Specificity:

ALDH1L1 polyclonal antibody detects endogenous levels of ALDH1L1 protein.

Alternative names:

10-FTHFDH, FDH, ALDH1L1, FTHFD, 10 formyltetrahydrofolate dehydrogenase, 10 FTHFDH, 10-formyltetrahydrofolate dehydrogenase, 10-FTHFDH, AL1L1, Aldehyde dehydrogenase 1 family member L1, Aldehyde dehydrogenase family 1 member L1, aldh1l1, Cytosolic 10-formyltetrahydrofolate dehydrogenase, DKFZp781N0997, EC 1.5.1.6, FDH, formyltetrahydrofolate dehydrogenase, FTHFD, OTTHUMP00000155221, OTTHUMP00000214696, OTTHUMP00000214700, OTTHUMP00000222724,

Species reactivity:

Human, Mouse, Rat

Host:

Rabbit

Ig type:

Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Immunogen:

Recombinant protein

Purification & Purity:

ProA affinity purified

Molecular weight:

99 kDa

Applications:

WB IHC

Usage:

WB:1:500-2,000 IHC:1:50-1:200

Storage:

Store at +4°C after thawing. Aliquot store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.

Precautions:

For research use only, not for use in diagnostic procedure.

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