Background:

ACTL6A also named BAF53. The SWI/SNF complex regulates gene expression via ATP-dependent chromatin remodeling. Brm (SNF2-a), Brg-1 (SNF2-b), Ini1 (integrase interactor 1, SNF5), BAF53 (ARPnβ), BAF57, BAF155 (SRG3), and BAF170 make up the functional core. BAF53 homologues from yeast to humans contain a conserved N-terminal motif, which contains residues at serine 2 and tyrosine 6, which play important roles in BAF53 activity. The BAF53 protein shuttles between the nucleus and cytoplasm. BAF53 also forms a complex with TIP49 and TIP48, which mediates c-Myc oncogenic activity.

Specificity:

ACTL6A polyclonal antibody detects endogenous levels of ACTL6A protein.

Alternative names:

BAF53A, ACTL6A, BAF53, BAF53A, INO80K, 53 kDa BRG1 associated factor A, 53 kDa BRG1-associated factor A, ACL6A, Actin like 6A, Actin like protein 6A, Actin related protein 4, Actin related protein, Actin related protein Baf53a, Actin-like protein 6A, Actin-related protein Baf53a, ACTL 6, ACTL 6A, ACTL6, ACTL6A, Arp4, ARPN BETA, ArpNbeta, BAF 53A, BAF complex 53 kDa subunit, BAF53, BAF53A, BRG1 associated factor, BRG1-associated factor 53A, hArpN beta, INO80 complex subunit K, INO80K, MGC5382,

Species reactivity:

Human, Mouse

Host:

Rabbit

Ig type:

Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Immunogen:

Recombinant protein

Purification & Purity:

ProA affinity purified

Molecular weight:

47 kDa

Applications:

WB ICC IF IHC IP

Usage:

WB:1:500-1:2,000 ICC/IF:1:50-1:100 IHC:1:50-1:100 IP:1:10-1:50

Storage:

Store at +4°C after thawing. Aliquot store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.

Precautions:

For research use only, not for use in diagnostic procedure.

More info:

Email: info@sobekbio.com

Orders:

Email: orders@sobekbio.com