Background:

The transcriptional enhancer factor (TEF)/TEAD family of proteins includes TEF-1, TEF-3, TEF-4 and TEF-5, all of which share a highly conserved 68 amino acid TEA/ATTS DNA-binding domain. TEF-5 (transcriptional enhancer factor-5), also known as TEAD3, TEAD5, DTEF-1 or ETFR-1, is a 435 amino acid nuclear protein that contains one TEA DNA-binding domain and belongs to the TEF transcriptional enhancer family. Expressed predominately in placental tissue and skeletal muscle, TEF-5 binds to multiple sites in the promotor of Placental lactogen II (also known as chorionic somatomammotropin-B) and, via this binding, enhances Placental lactogen II transcription. Due to its ability to enhance the expression of placenta-related genes, TEF-5 is thought to function as an important regulatory protein within the human placenta.

Specificity:

TEF-5 polyclonal antibody detects endogenous levels of TEF-5 protein.

Alternative names:

Transcriptional enhancer factor TEF-5; DTEF-1; TEA domain family member 3; TEAD-3; TEAD3; TEAD5; TEF5

Species reactivity:

Human,Mouse

Host:

Rabbit

Ig type:

Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Immunogen:

Recombinant full length Human TEF-5.

Purification & Purity:

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Molecular weight:

~ 49kDa

Applications:

WB IHC IF

Usage:

WB 1:500 - 1:2000 IHC 1:50 - 1:200 IF 1:50 - 1:200

Storage:

Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Precautions:

For research use only, not for use in diagnostic procedure.

More info:

Email: info@sobekbio.com

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