Background:

The Ca2+/calmodulin-dependent protein kinases (CaMKs) comprise a structurally related subfamily of serine/threonine kinases. CaMKIγ (calcium/calmodulin-dependent protein kinase Iγ), also known as VWS1 or CLICKIII, is a 476 amino acid protein that localizes to both the cytoplasm and to the membrane of the Golgi apparatus and contains one protein kinase domain. Expressed predominately in brain and present at lower levels in spleen, liver, kidney and skeletal muscle, CaMKIγ functions as a Ca2+/calmodulin-dependent protein kinase that uses ATP to catalyze the phosphorylation of target proteins, such as the transcription factpr CREB-1. CaMKIγ exists as multiple alternatively spliced isoforms and is encoded by a gene which maps to human chromosome 1.

Specificity:

CAMK1G polyclonal antibody detects endogenous levels of CAMK1G protein.

Alternative names:

Calcium/calmodulin-dependent protein kinase type 1G; CaM kinase I gamma; CaM kinase IG; CaM-KI gamma; CaMKI gamma; CaMKIG; CaMK-like CREB kinase III; CLICK III; CAMK1G; CLICK3, VWS1

Species reactivity:

Human,Mouse,Rat

Host:

Rabbit

Ig type:

Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Immunogen:

Recombinant full length Human CAMK1G.

Purification & Purity:

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Molecular weight:

~ 53kDa

Applications:

WB IHC

Usage:

WB: 1:500~1:2000 IHC: 1:50~1:200

Storage:

Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Precautions:

For research use only, not for use in diagnostic procedure.

More info:

Email: info@sobekbio.com

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