Background:

THADA (thyroid adenoma associated), also known as GITA, is a 1,953 amino acid protein that is expressed in testis, thyroid, pancreas, stomach and small intestine. Chromosomal aberrations in the gene encoding THADA are associated with benign thyroid adenomas, suggesting a potential role for THADA in tumorigenesis. The THADA gene maps to human chromosome 2, which houses over 1,400 genes and comprises nearly 8% of the human genome. Harlequin icthyosis, a rare and morbid skin deformity, is associated with mutations in the chromosome 2-localized ABCA12 gene, while the lipid metabolic disorder sitosterolemia is associated with defects in the ABCG5 and ABCG8 genes, which also map to chromosome 2.

Specificity:

THADA polyclonal antibody detects endogenous levels of THADA protein.

Alternative names:

Thyroid adenoma-associated protein; Gene inducing thyroid adenomas protein; THADA; GITA, KIAA1767

Species reactivity:

Human,Mouse

Host:

Rabbit

Ig type:

Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Immunogen:

Recombinant full length Human THADA.

Purification & Purity:

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Molecular weight:

~ 220kDa

Applications:

WB IF

Usage:

WB 1:500 - 1:2000 IF 1:50 - 1:100

Storage:

Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Precautions:

For research use only, not for use in diagnostic procedure.

More info:

Email: info@sobekbio.com

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