Background:

GTL3 (gene trap locus 3), also known as EVORF, fSAP23, C16orf80 or transcription factor IIB, is a 193 amino acid protein belonging to the UPF0468 family and may be involved in transcriptional regulation. The gene encoding GTL3 maps to human chromosome 16, which is associated with a variety of genetic disorders, encodes over 900 genes and comprises nearly 3% of the human genome. The GAN gene is located on chromosome 16 and, with mutation, may lead to giant axonal neuropathy, a nervous system disorder characterized by increasing malfunction with growth. The rare disorder Rubinstein-Taybi syndrome is associated with chromosome 16, as is Crohn's disease, which is a gastrointestinal inflammatory condition.

Specificity:

C16orf80 polyclonal antibody detects endogenous levels of C16orf80 protein.

Alternative names:

Cilia- and flagella-associated protein 20; Basal body up-regulated protein 22; Transcription factor IIB; CFAP20; BUG22; C16orf80

Species reactivity:

Human,Mouse,Rat

Host:

Rabbit

Ig type:

Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Immunogen:

Recombinant full length Human C16orf80.

Purification & Purity:

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Molecular weight:

~ 23kDa

Applications:

WB IF

Usage:

WB: 1:500~1:2000 IF: 1:50~1:200

Storage:

Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Precautions:

For research use only, not for use in diagnostic procedure.

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