Background:

MTF-2 (metal response element binding transcription factor 2), also known as PCL2 (polycomb-like protein 2) or metal-response element DNA-binding protein M96, is a 593 amino acid nuclear protein that binds the metal-regulatingelement (MRE) of the gene promoter for Metallothionein 1A. Containing two PHD-type zinc fingers, MTF-2 exists as three alternatively spliced isoforms and is encoded by a gene that maps to human chromosome 1p22.1. Human chromosome 1 spans 260 million base pairs, contains over 3,000 genes, comprises nearly 8% of the human genome and houses a large number of diseaseassociated genes, including those that are involved in familial adenomatous polyposis, Stickler syndrome, Parkinson’s disease, Gaucher disease, schizophrenia and Usher syndrome.

Specificity:

MTF2 polyclonal antibody detects endogenous levels of MTF2 protein.

Alternative names:

Metal-response element-binding transcription factor 2; Metal regulatory transcription factor 2; Metal-response element DNA-binding protein M96; Polycomb-like protein 2; hPCl2; MTF2; PCL2

Species reactivity:

Human,Mouse,Rat

Host:

Rabbit

Ig type:

Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Immunogen:

Recombinant full length Human MTF2.

Purification & Purity:

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Molecular weight:

~ 67kDa

Applications:

WB IF

Usage:

WB: 1:500~1:2000 IF: 1:50~1:200

Storage:

Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Precautions:

For research use only, not for use in diagnostic procedure.

More info:

Email: info@sobekbio.com

Orders:

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