Background:

SMPX (small muscle protein, X-linked), also known as SRMX, is an 86 amino acid protein that is preferentially expressed at high levels in heart and skeletal muscle where it is thought to play a role in muscle structure during growth, repair and adaptation. Defects in the gene encoding SMPX, which maps to human chromosome X, may play a role in the development of X-linked cardiac or muscle disorders. Chromosome X, one of the two human sex chromosomes, contains nearly 153 million base pairs and encodes over 1,000 genes. In conjunction with chromosome Y, chromosome X is responsible for sex determination, as an X and a Y chromosome lead to normal male development, while two copies of an X chromosome lead to normal female development. There are a number of conditions related to an abnormal number and combination of sex chromosomes , some of which include Turner's syndrome, color blindness, hemophilia and Duchenne muscular dystrophy.

Specificity:

SMPX polyclonal antibody detects endogenous levels of SMPX protein.

Alternative names:

Small muscular protein; Stretch-responsive skeletal muscle protein; SMPX; SRMX

Species reactivity:

Human,Mouse,Rat

Host:

Rabbit

Ig type:

Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Immunogen:

Recombinant full length Human SMPX.

Purification & Purity:

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Molecular weight:

~ 10 kDa

Applications:

WB IF

Usage:

WB 1:500 - 1:2000 IF 1:50 - 1:100

Storage:

Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Precautions:

For research use only, not for use in diagnostic procedure.

More info:

Email: info@sobekbio.com

Orders:

Email: orders@sobekbio.com