Background:

Ribosomes, the organelles that catalyze protein synthesis, are composed of a small subunit (40S) and a large subunit (60S) that consist of over 80 distinct ribosomal proteins. Mammalian ribosomal proteins are encoded by multigene families that contain processed pseudogenes and one functional intron-containing gene within their coding regions. Ribosomal Protein S7, also known as RPS7, is a 194 amino acid protein that is a component of the 40S subunit. Localized to the cytoplasm, Ribosomal Protein S7 belongs to the S7e family of ribosomal proteins and functions in protein synthesis. Ribosomal Protein S7 interacts with MDM2 and is believed to negatively regulate the MDM2-mediated degradation of p53. In addition, Ribosomal Protein S7 may play a role in ribosomal stress, linking ribosome biogenesis to cell death or cell cycle arrest. Like most ribosomal proteins, Ribosomal Protein S7 exists as multiple processed pseudogenes that are scattered throughout the genome.

Specificity:

RPS7 polyclonal antibody detects endogenous levels of RPS7 protein.

Alternative names:

40S ribosomal protein S7; RPS7

Species reactivity:

Human,Mouse,Rat

Host:

Rabbit

Ig type:

Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Immunogen:

Recombinant full length Human RPS7.

Purification & Purity:

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Molecular weight:

~ 22 kDa

Applications:

WB IHC IF

Usage:

WB 1:500 - 1:2000 IHC 1:50 - 1:200 IF 1:10 - 1:100

Storage:

Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Precautions:

For research use only, not for use in diagnostic procedure.

More info:

Email: info@sobekbio.com

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