Background:

Ribosomes, the organelles that catalyze protein synthesis, are composed of a small subunit (40S) and a large subunit (60S) that consist of over 80 distinct ribosomal proteins. Mammalian ribosomal proteins are encoded by multigene families that contain processed pseudogenes and one functional intron-containing gene within their coding regions. Ribosomal Protein LP1 (ribosomal protein, large, P1), also known as 60S acidic ribosomal protein P1, RPP1 or RPLP1, is a 114 amino acid acidic protein that belongs to the ribosomal protein L12P family. A key component during the elongation step of protein synthesis, Ribosomal Protein LP1 forms a pentameric complex (in conjunction with LP2 and LP0) that regulates ribosome assembly and plays a role in translation initiation. Like other mammalian ribosomal proteins, Ribosomal Protein LP1 exists as multiple processed pseudogenes that are found throughout the genome.

Specificity:

RPLP1 polyclonal antibody detects endogenous levels of RPLP1 protein.

Alternative names:

60S acidic ribosomal protein P1; RPLP1; RRP1

Species reactivity:

Human,Mouse,Rat

Host:

Rabbit

Ig type:

Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Immunogen:

Recombinant full length Human RPLP1.

Purification & Purity:

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Molecular weight:

~ 12 kDa

Applications:

WB IHC IF

Usage:

WB: 1:500~1:2000 IHC/IF: 1:50~1:200

Storage:

Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Precautions:

For research use only, not for use in diagnostic procedure.

More info:

Email: info@sobekbio.com

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